2-Methyltetrahydrofuran (MeTHF) is a green solvent used in the pharmaceutical industry in organometallic reactions and as an extraction solvent. It is a green and less toxic alternative for Tetrahydorfuran and has multiple superior properties. It also has potential in alternative fuels.


MeTHF in practice

MeTHF’s main application is to replace Tetrahydrofuran (THF) in solvent applications. MeTHF is a green alternative, is less toxic and has multiple performance advantages compared to THF. The higher boiling point and azeotrope with water gives econominc benefits in the use as a solvent in many applications. In Grignard reactions to manufacture API’s higher yiels can be achieved as an additional benefit over traditional solvents.



Chemical name 2-Methyltetrahydrofuran
CAS number 96-47-9
2-Methyltetrahydrofuran purity (%) min. 99.9
BHT inhibitor content (ppm) 150-400
Moisture content (wt%) max. 0.03
Peroxides [ppm] max. 15
APHA colour max. 20
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